Fluasterone

CAS : 112859-71-9

Ref. TR-F500300

Informations sur le produit

• Nom: Fluasterone
• Synonymes: (8R,9S,10R,13S,14S,16R)-16-fluoro-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one, (16Alpha)-16-Fluoroandrost-5-En-17-One, (16α)-16-Fluoroandrost-5-en-17-one, (8R,9S,10R,13S,14S)-16-fluoro-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one, 16alpha-Fluoro-5-androsten-17-one, 16α-Fluoro-5-androsten-17-one, Androst-5-en-17-one, 16-fluoro-, (16alpha)-, Androst-5-en-17-one, 16-fluoro-, (16α)-, Ccris 4216

Description

Applications A synthetic derivative of Dehydroepiandrosterone. The reduced androgenicity of Fluasterone may obviate toxicities associated with the androgenicity of the parent compound. Antitumor agent. Used in clinical trials for prostate cancer prevention.
References Bentley, P., et al.: Food Chem. Toxicol., 31, 857 (1993), Rao, K., et al.: Cancer Res., 59, 3084 (1999), Masuzaki, H., et al.: Science, 294, 2166 (2001), Osawa, E., et al.: Life Sci., 70, 2623 (2002),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 290.42
• Formule: C₁₉H₂₇FO
• Couleur/Forme: Neat
• InChI: InChI=1S/C19H27FO/c1-18-9-4-3-5-12(18)6-7-13-14(18)8-10-19(2)15(13)11-16(20)17(19)21/h6,13-16H,3-5,7-11H2,1-2H3/t13-,14+,15+,16-,18+,19+/m1/s1
• Code InChI: InChIKey=VHZXNQKVFDBFIK-NBBHSKLNSA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CC=C4CCCC[C@@]43C)[C@@H]1C[C@@H](F)C2=O