(S)-N-Fmoc-N6,N6-dimethyl-L-lysine Hydrochloride

CAS : 252049-10-8

Ref. TR-F648400

Informations sur le produit

• Nom: (S)-N-Fmoc-N6,N6-dimethyl-L-lysine Hydrochloride
• Synonymes: N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6,N6-dimethyl-L-Lysine Hydrochloride, (S)-N-Fmoc-N',N''-dimethyl-L-lysine Hydrochloride, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N',N'-dimethyl-L-lysine hydrochloride, Fmoc-Lys(Me)2-OH HCl, Fmoc-Lys(Me2)-OH.HCL, Fmoc-Lys(Me)2-OH・HCl

Description

Applications Di-Me L-lysine derivative. The methylation of lysine in histone tails is a common posttranslational modification that functions in histone-regulated chromatin condensation, with binding of methylated lysine occurring in aromatic pockets on chromodomain proteins.
References Schreiber, G., et al.: J. Mol. Biol., 248, 478 (1995), Jacobs, S., et al.: Science, 295, 2080 (2002), Tatko, C., et al.: Protein Sci., 12, 2443 (2003),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 432.94
• Formule: C₂₃H₂₈N₂O₄·ClH
• Couleur/Forme: Neat
• InChI: InChI=1S/C23H28N2O4.ClH/c1-25(2)14-8-7-13-21(22(26)27)24-23(28)29-15-20-18-11-5-3-9-16(18)17-10-4-6-12-19(17)20;/h3-6,9-12,20-21H,7-8,13-15H2,1-2H3,(H,24,28)(H,26,27);1H/t21-;/m0./s1
• Code InChI: InChIKey=SJFAFKDBWNFBCC-BOXHHOBZSA-N
• SMILES: CN(C)CCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.Cl