2-Furoylglycine

CAS : 5657-19-2

Ref. TR-F865225

Informations sur le produit

• Nom: 2-Furoylglycine
• Synonymes: Glycine, N-2-furoyl- (8CI), N-(2-Furanylcarbonyl)glycine, 2-Furancarboxamide, N-(carboxymethyl)-, 2-[(Furan-2-carbonyl)amino]acetic acid, Furfuroylglycine, Furoylglycine, N-(2-Furoyl)glycine, Pyromucuric acid, [(Furan-2-carbonyl)amino]acetic acid, [[(Furan-2-yl)carbonyl]amino]acetic acid, (2Z)-2-[(2-methylphenyl)hydrazono]-1-benzothiophen-3(2H)-one, 2-(2-Furoylamino)acetic acid, 2-(Furan-2-ylformamido)acetic acid, 2-Furancarboxamide, N-(carboxymethyl)-, 2-[(Furan-2-yl)formamido]acetic acid, Brn 0142378, Furoilglicina, Furoilglicina [Italian], Glycine, N-(2-furanylcarbonyl)-, Glycine, N-(2-furanylcarbonyl)- (9CI), Glycine, N-2-furoyl-, N-(furan-2-ylcarbonyl)glycine

Description

Applications 2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.
References Antonysamy, S., et al.: Bioorg. Med. Chem. Lett., 18, 2990 (2008); Kazmierski, W., et al.: PCT Int. Appl. (2004), WO 2004054974 A2 20040701

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 169.13
• Formule: C₇H₇NO₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C7H7NO4/c9-6(10)4-8-7(11)5-2-1-3-12-5/h1-3H,4H2,(H,8,11)(H,9,10)
• Code InChI: InChIKey=URHVSGAXRNLQCN-IVYNGHAPSA-N
• SMILES: CO[C@@H]1OC2COC(c3ccccc3)O[C@@H]2C(O[C@@H]2OC(CO)[C@H](O)C(O)C2O)C1O