21-​Hemiacetal dexamethasone

CAS : 473273-03-9

Ref. TR-H235320

Informations sur le produit

• Nom: 21-​Hemiacetal dexamethasone
• Synonymes: (11ß,?16a)?-9-?Fluoro-?11,?17,?21-?trihydroxy-?21-?methoxy-?16-?methyl-pregna-?1,?4-?diene-?3,?20-?dione

Description

Applications 21-​Hemiacetal dexamethasone is an impurity of dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 422.49
• Formule: C₂₃H₃₁FO₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C23H31FO6/c1-12-9-16-15-6-5-13-10-14(25)7-8-20(13,2)22(15,24)17(26)11-21(16,3)23(12,29)18(27)19(28)30-4/h7-8,10,12,15-17,19,26,28-29H,5-6,9,11H2,1-4H3/t12-,15+,16+,17+,19?,20+,21+,22+,23+/m1/s1
• Code InChI: InChIKey=UCCNAQVBEVBWAA-HIAQARTRSA-N
• SMILES: COC(O)C(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C