(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol

CAS : 156928-09-5

Ref. TR-H291095

Informations sur le produit

• Nom: (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol
• Synonymes: [3R-(3alpha,3abeta,6abeta)]-Hexahydrofuro[2,3-b]furan-3-ol, R,S,R-Bisfuran Alcohol, Furo[2,3-b]furan-3-ol, hexahydro-, (3R,3aS,6aR)-, Furo[2,3-b]furan-3-ol, hexahydro-, [3R-(3α,3aβ,6aβ)]-, Hexahydro-(3R,3aS,6aR)-furo(2,3-b)furan-3-ol, R,S,R-Bisfuran alcohol

Description

Applications (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol is used as a reagent in the synthesis of Darunavir (D193500); a second generation HIV-1-protease inhibitor and antiviral agent.
References Canoy, W.L., et al.: Org. Lett., 10, 1103 (2008); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 130.14
• Formule: C₆H₁₀O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C6H10O3/c7-5-3-9-6-4(5)1-2-8-6/h4-7H,1-3H2/t4-,5-,6+/m0/s1
• Code InChI: InChIKey=RCDXYCHYMULCDZ-HCWXCVPCSA-N
• SMILES: O[C@H]1CO[C@H]2OCC[C@@H]12