Homoharringtonine

CAS : 26833-87-4

Ref. TR-H596500

Informations sur le produit

• Nom: Homoharringtonine
• Synonymes: Cephalotaxine, 3-[4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate], Cephalotaxine, 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (ester) (9CI), Homoharringtonine (8CI), CGX 635, Ceflatonin, Myelostat, NSC 141633, Omacetaxine mepesuccinate, Synribo
• Marque: TRC
• Description: Applications Homoharringtonine (HHT) combined with some botanical drugs could induce cancer cells to resemble normal cells. HHT was prepared by a semi-synthetic method from Cephalotaxine, a major alkaloid of Cepahlotaxus species through the formation of α-ketoester harringtonine. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Baaske, D., et al.: Antimicrob. Agents Chemother., 12, 298 (1977), Tipping, A., et al.: Leukemia, 16, 2349 (2002), Marin, D., et al.: Cancer, 103, 1850 (2005), Levy, V., et al.: Br. J. Cancer, 95, 253 (2006), de Lavallade, H., et al.: Blood, 2779 (2007),

Propriétés chimiques

• Masse moléculaire: 545.62
• Formule: C₂₉H₃₉NO₉
• Couleur/Forme: Neat
• InChI: InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1
• Code InChI: InChIKey=HYFHYPWGAURHIV-ZEDNPHJLSA-N
• SMILES: COC(=O)CC(O)(CCCC(C)(C)O)C(=O)O[C@@H]1C(OC)=C[C@]23CCCN2CCc2cc4c(cc2[C@@H]13)OCO4