m-Hydroxycocaine-D3

CAS : 253775-19-8

Ref. TR-H825444

Informations sur le produit

• Nom: m-Hydroxycocaine-D3
• Synonymes: (1R,2R,3S,5S)-3-[(3-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester-D3,[1R-(exo,exo)]-3-[(3-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester-D3, 3'-Hydroxybenzoylecgonine Methyl Ester-D3, 3'-Hydroxycocaine-D3
• CAS: 253775-19-8

Description

Applications m-Hydroxycocaine-D3 is a labelled analogue of m-Hydroxycocaine (H825440). m-Hydroxycocaine is a metabolite of Cocaine (HCl: C633500), a vasoconstrictive agent that is highly addictive and has high potential for abuse. The mechanism by which Cocaine induces dependence is unknown, but it is hypothesized that it works by blocking the dopamine transporter, increasing the amount of free dopamine in the brain.
References Carrera, M., et al.: Nature, 378, 727 (1995); Moore, T., et al.: Am. J. Obst. Gyne., 155, 883 (1986); Volkow, N., et al.: Nature, 386, 827 (1997)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 322.38
• Formule: C₁₇H₁₈D₃NO₅
• Couleur/Forme: White to Off-White Solid
• InChI: InChI=1S/C17H21NO5/c1-18-11-6-7-13(18)15(17(21)22-2)14(9-11)23-16(20)10-4-3-5-12(19)8-10/h3-5,8,11,13-15,19H,6-7,9H2,1-2H3/t11-,13+,14-,15+/m0/s1/i1D3
• Code InChI: InChIKey=IQXBUEUAOWARGT-ZRYGNULPSA-N
• SMILES: [2H]C([2H])([2H])N1[C@H]2CC[C@@H]1[C@@H](C(=O)OC)[C@@H](OC(=O)c1cccc(O)c1)C2