8-Hydroxy-3,4-dihydroquinolin-2-oxo-indacaterol

CAS : 1403389-05-8

Ref. TR-H834240

Informations sur le produit

• Nom: 8-Hydroxy-3,4-dihydroquinolin-2-oxo-indacaterol
• Synonymes: (R)-5-(2-((5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-8-hydroxy-3,4-dihydroquinolin-2(1H)-one, Indacaterol Impurity 1
• CAS: 1403389-05-8

Description

Applications 8-Hydroxy-3,4-dihydroquinolin-2-oxo-Indacaterol is an impurity of Indacaterol(I499745) which is a β-adrenoreceptor agonists for treatment of asthma and bronchodilator treatment for patients with chronic obstructive pulmonary diseases.
References Crisafulli, E., et al.; Expert Opinion Pharmacother., 18, 1499 (2017); Aparici, M., et al.: Pul. Pharmacol. Ther., 46, 1 (2017); Demin, I., et al.: Int. J. Clin. Pharmacol. Ther., 54, 405 (2016)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 394.51
• Formule: C₂₄H₃₀N₂O₃
• Couleur/Forme: Pale Orange to Pale Brown Solid
• InChI: InChI=1S/C24H30N2O3/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24/h5,7,9-10,18,22,25,27-28H,3-4,6,8,11-13H2,1-2H3,(H,26,29)/t22-/m0/s1
• Code InChI: InChIKey=CEVVMMPBOCCERE-QFIPXVFZSA-N
• SMILES: CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3c1CCC(=O)N3)C2