25-Hydroxy Cholesterol

CAS : 2140-46-7

Ref. TR-H918030

Informations sur le produit

• Nom: 25-Hydroxy Cholesterol
• Synonymes: Cholest-5-ene-3,25-diol, (3ß)-, Cholest-5-ene-3ß,25-diol (8CI), (3ß)-Cholest-5-ene-3,25-diol, 25-Hydroxy-5-cholestene-3ß-ol, 25-Hydroxycholesterol, 5-Cholesten-3ß,25-diol, (3β)-Cholest-5-ene-3,25-diol, 25-Hydroxy-5-cholestene-3β-ol, 5-Cholesten-3β,25-diol, Cholest-5-ene-3,25-diol, (3β)-, Cholest-5-ene-3β,25-diol

Description

Applications An oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.
References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 402.65
• Formule: C₂₇H₄₆O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1
• Code InChI: InChIKey=INBGSXNNRGWLJU-ZHHJOTBYSA-N
• SMILES: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C