3Alpha-Hydroxydesoxy Artemether

CAS : 174097-70-2

Ref. TR-H939050

Informations sur le produit

• Nom: 3Alpha-Hydroxydesoxy Artemether
• Synonymes: (2S,3R,3aS,6R,6aS,8R,9S,10aR,10bR)-Decahydro-2-methoxy-3,6,9-trimethyl-10aH-9,10b-epoxypyrano[4,3,2-jk][2]benzoxepin-8-ol, 3alpha-Hydroxydeoxyartemether,[2S-(2alpha,3alpha,3abeta,6beta,6abeta,8beta,9beta,10aalpha,10bbeta)]-Decahydro-2-methoxy-3,6,9-trimethyl-10aH-9,10b-Epoxypyrano[4,3,2-jk][2]benzoxepin-8-ol
• CAS: 174097-70-2

Description

Applications A metabolite of Artemether (A777400) and derivative of the antimalarial drug Artemisinin (A777500). Studies suggest that it may display neurotoxicity in animals due to its interaction with iron.
References Smith, S.L. et al.: Neurotoxicology, 19, 557 (1998); Abourashed, E.A. et al.: J. Natur. Prod., 59, 251 (1996);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 298.375
• Formule: C₁₆H₂₆O₅
• InChI: InChI=1S/C16H26O5/c1-8-5-6-10-9(2)13(18-4)19-14-16(10)11(8)7-12(17)15(3,20-14)21-16/h8-14,17H,5-7H2,1-4H3/t8-,9-,10+,11+,12-,13-,14+,15-,16+/m1/s1
• Code InChI: InChIKey=NYMSZZKRBMNKGP-YMSVXTLUSA-N
• SMILES: CO[C@@H]1O[C@H]2O[C@]3(C)O[C@@]24[C@@H](C[C@H]3O)[C@H](C)CC[C@H]4[C@H]1C