Hydroxy Ibuprofen

CAS : 53949-54-5

Ref. TR-H943200

Informations sur le produit

• Nom: Hydroxy Ibuprofen
• Synonymes: Benzeneacetic acid, 4-(3-hydroxy-2-methylpropyl)-a-methyl-, 2-[4-(3-Hydroxy-2-methyl-propyl)phenyl]propanoic acid, 4-(3-Hydroxy-2-methylpropyl)-a-methylbenzeneacetic acid, 2,4'-(2-Hydroxymethylpropyl)phenylpropionic acid, 2-[4-(2-Hydroxymethylpropyl)phenyl]propanoic acid, 3-Hydroxyibuprofen
• CAS: 53949-54-5

Description

Applications Hydroxy Ibuprofen is a metabolite of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); Neunzig, I. et al.: J. Biotechnol., 157, 417 (2012);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 222.28
• Formule: C₁₃H₁₈O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C13H18O3/c1-9(8-14)7-11-3-5-12(6-4-11)10(2)13(15)16/h3-6,9-10,14H,7-8H2,1-2H3,(H,15,16)
• Code InChI: InChIKey=HFAIHLSDLUYLQA-UHFFFAOYSA-N
• SMILES: CC(CO)Cc1ccc(C(C)C(=O)O)cc1