D-p-Hydroxyphenylglycinamide (>85%)

CAS : 54397-23-8

Ref. TR-H951320

Informations sur le produit

• Nom: D-p-Hydroxyphenylglycinamide (>85%)
• Synonymes: (2R)-2-Amino-2-(4-hydroxyphenyl)acetamide
• CAS: 54397-23-8

Description

Applications D-p-Hydroxyphenylglycinamide is an activated side chain precursor and is an intermediate in the synthesis of 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (H951260), which is a potential impuritiy of the penicillins, ampicillin and amoxicillin, which have not been reported previously. 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone impurity may be formed during the semi-synthetic preparation of these antibiotics or upon their degradation.
References Munro, A., et al.: J. Pharm. Sci., 67, 1197 (1978); Lebelle, M., et al.: J. Pharm. Pharmacol., 31, 441 (1979); Gabor, E., et al.: PCT Int. Appl., WO 2004111241 A1 20041223 (2004)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 166.18
• Formule: C₈H₁₀N₂O₂
• Degré de pureté: >85%
• Couleur/Forme: Neat
• InChI: InChI=1S/C8H10N2O2/c9-7(8(10)12)5-1-3-6(11)4-2-5/h1-4,7,11H,9H2,(H2,10,12)/t7-/m1/s1
• Code InChI: InChIKey=WQFROZWIRZWMFE-SSDOTTSWSA-N
• SMILES: NC(=O)[C@H](N)c1ccc(O)cc1