2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)propanoic Acid Hydrochloride

CAS : 185066-33-5

Ref. TR-H954043

Informations sur le produit

• Nom: 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)propanoic Acid Hydrochloride
• Synonymes: Fexofenadine Impurity F

Description

Applications 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)propanoic Acid is an impurity of Fexofenadine (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.
References Pratt, E., et al.: Diabet Med., 18, 515 (2001), Mizutani, N., et al.: J. Pharmacol. Sci., 93, 437 (2003), Scadding, G., et al.: Clin. Drug Invest., 25, 153 (2005), Asai, M., et al.: N. Engl. J. Med., 354, 307 (2006),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 487.63 + (36.46)
• Formule: C₃₁H₃₇NO₄·HCl
• Couleur/Forme: Neat
• InChI: InChI=1S/C31H37NO4.ClH/c1-23(30(34)35)24-14-16-25(17-15-24)29(33)13-8-20-32-21-18-28(19-22-32)31(36,26-9-4-2-5-10-26)27-11-6-3-7-12-27;/h2-7,9-12,14-17,23,28-29,33,36H,8,13,18-22H2,1H3,(H,34,35);1H
• Code InChI: InChIKey=XHSWEQXJKSQVRA-UHFFFAOYSA-N
• SMILES: CC(C(=O)O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1.Cl