(S)-7-Hydroxy Warfarin

CAS : 63740-81-8

Ref. TR-H996126

Informations sur le produit

• Nom: (S)-7-Hydroxy Warfarin
• Synonymes: 2H-1-Benzopyran-2-one, 4,7-dihydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-, 2H-1-Benzopyran-2-one, 4,7-dihydroxy-3-(3-oxo-1-phenylbutyl)-, (S)-, 4,7-Dihydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one, 7-Hydroxy-S-warfarin, S-7-Hydroxywarfarin, (S)-7-Hydroxywarfarin
• CAS: 63740-81-8

Description

Applications (S)-7-Hydroxywarfarin is the S-enantiomer of the 7-hydroxyl metabolite of Warfarin (W498500). (S)-7-Hydroxy Warfarin was present at levels 7-folds higher in chimeric mice with humanized liver (than that in controlled mice) following (S)-Warfarin metabolism.
References Wong, Y.W.J. et al.: Pharm. Res., 6, 982 (1989); O'Reilly, R.A. et al.: Clin. Pharmacol. Ther., 51, 656 (1992); Inoue, T. et al: Drug Metab. Dispos. 36, 2429 (2008);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 324.33
• Formule: C₁₉H₁₆O₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C19H16O5/c1-11(20)9-15(12-5-3-2-4-6-12)17-18(22)14-8-7-13(21)10-16(14)24-19(17)23/h2-8,10,15,21-22H,9H2,1H3/t15-/m0/s1
• Code InChI: InChIKey=SKFYEJMLNMTTJA-HNNXBMFYSA-N
• SMILES: CC(=O)C[C@@H](c1ccccc1)c1c(O)c2ccc(O)cc2oc1=O