Indigopurpurin

CAS : 479-41-4

Ref. TR-I521350

Informations sur le produit

• Nom: Indigopurpurin
• Synonymes: (3E)-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one, (2Z)-2,3'-biindole-2',3(1H,1'H)-dione, 2,3'-biindole-2',3(1H,1'H)-dione, 2-(2-Oxo-1H-Indol-3-Ylidene)-1H-Indol-3-One, 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-, 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one, Couroupitine B, Indigo red, NSC 105327, [Δ^2,3′-Biindoline]-2′,3-dione, [Δ2,3′-Biindoline]-2′,3-dione, Indirubin, C.I. 73200

Description

Applications Indigopurpurin is a purple 3,2-bisindole derivative and was shown to exhibit inhibitory allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model. A possible glycogen synthase kinase-3 (GSK-3) inhibitor the active component of a traditional Congolese antiepilepsy treatment.
References Kim, M.H., et al.: J. Ethnopharmacol., 145, 214 (2013); Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Hsieh, W.L., et al.: J. Dermatol. Sci., 67, 140 (2012); Chem. and Eng. News page 6 Nov. 10 (2018)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 262.26
• Formule: C₁₆H₁₀N₂O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13+
• Code InChI: InChIKey=CRDNMYFJWFXOCH-YPKPFQOOSA-N
• SMILES: O=C1Nc2ccccc2/C1=C1/Nc2ccccc2C1=O