myo-Inositol-d6 Trispyrophosphate Hexasodium Salt

CAS : 23103-35-7

Ref. TR-I666022

Informations sur le produit

• Nom: myo-Inositol-d6 Trispyrophosphate Hexasodium Salt
• Synonymes: ITTP-d6 Hexasodium Salt, myo-Inositol-d6 Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) Hexasodium Salt, myo-Inositol-d6 Cyclic 1,2:3,4:5,6-Tris(P,P'-dihydrogen diphosphate) Hexasodium Salt, ITTP Hexasodium Salt, Itpp Sodium Salt

Description

Applications Labelled myo-Inositol Trispyrophosphate hexasodium (I666020). A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such as cancer and cardiovascular ailments.
References Duarte,C.D. et al.: Chembiochem., 11, 2543 (2010); Biolo, A. et al.: Proc. Nat. Acad. Sci. U.S.A., 106, 1926 (2009);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 743.92
• Formule: C₆D₆Na₆O₂₁P₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C6H12O21P6.6Na/c7-28(8)19-1-2(20-29(9,10)25-28)4-6(24-33(17,18)27-32(15,16)23-4)5-3(1)21-30(11,12)26-31(13,14)22-5;;;;;;/h1-6H,(H,7,8)(H,9,10)(H,11,12)(H,13,14)(H,15,16)(H,17,18);;;;;;/q;6*+1/p-6/t1-,2-,3-,4+,5-,6-;;;;;;/m0....../s1/i1D,2D,3D,4D,5D,6D
• Code InChI: InChIKey=DTOYSAZRROROSE-HOLNPVTASA-H
• SMILES: [2H][C@]12OP(=O)(O[Na])OP(=O)(O[Na])O[C@]1([2H])[C@@]1([2H])OP(=O)(O[Na])OP(=O)(O[Na])O[C@]1([2H])[C@@]1([2H])OP(=O)(O[Na])OP(=O)(O[Na])O[C@@]21[2H]