2-Iodo Adenosine35109-88-7

CAS : 35109-88-7

Ref. TR-I686000

Informations sur le produit

• Nom: 2-Iodo Adenosine35109-88-7
• Synonymes: (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, Adenosine, 2-iodo-

Description

Applications An intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxyadenosine), a naturally occuring nucleoside analogue of guanosine. Isoguanosine is incorporated into mammalian but not bacterial nucleic acids, stimulates the accumulation of cyclic AMP in the brain, and is an inhibitor of IMP:pyrophosphorylase.
References Lowry, B.A., et al.: J. Biol. Chem., 197, 591 (1952), Huang, M., et al.: J. Med. Chem., 15, 462 (1972), Hagen, C., et al.: Biochem. Biophys. Acta, 293, 105 (1973),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 393.14
• Formule: C₁₀H₁₂IN₅O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C10H12IN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
• Code InChI: InChIKey=MGEBVSZZNFOIRB-UUOKFMHZSA-N
• SMILES: Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O