1-Iodo-3-nitrobenzene

CAS : 645-00-1

Ref. TR-I715615

Informations sur le produit

• Nom: 1-Iodo-3-nitrobenzene
• Synonymes: 3-Iodo-1-nitrobenzene, 3-Iodonitrobenzene, 3-Nitro-1-iodobenzene, 3-Nitroiodobenzene, 3-Nitrophenyl Iodide, NSC 3538, m-Iodonitrobenzene, m-Nitroiodobenzene, m-Nitrophenyl Iodide
• Marque: TRC

Description

Applications 1-Iodo-3-nitrobenzene is a reactant used int he synthesis of Vismodegib (V674700), an, antineoplastic drug that targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cao, M., et. al.: Chem. Papers, 68, 1408 (2014); Gupta, S. et al.: Ther. Advances in Med. Oncology 2,237(2010)

Propriétés chimiques

• Masse moléculaire: 249.01
• Formule: C₆H₄INO₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C6H4INO2/c7-5-2-1-3-6(4-5)8(9)10/h1-4H
• Code InChI: InChIKey=OBQFYRYCMDREFB-AKIFATBCSA-N
• SMILES: O=C1[C@H](CC[C@H](O)c2ccccc2F)[C@@H](c2ccc(O)cc2)N1c1ccc(F)cc1