2-Isobutyryl-N-phenyl-3-phenylacrylamide

CAS : 265989-32-0

Ref. TR-I781042

Informations sur le produit

• Nom: 2-Isobutyryl-N-phenyl-3-phenylacrylamide
• Synonymes: 4-Methyl-3-oxo-N-(phenyl-d5)-2-(phenylmethylene)pentanamide
• Marque: TRC
• Description: Applications 2-Isobutyryl-N-phenyl-3-phenylacrylamide is the labeled analogue of 2-Isobutyryl-N-phenyl-3-phenylacrylamide (I781040), an intermediate for the synthesis of Atorvastatin-d5 Sodium Salt (A791753), the labeled analogue of Atorvastatin (A791750) (1,2,3). Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences (1) Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993) (2) Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996) (3) Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)

Propriétés chimiques

• Masse moléculaire: 298.39
• Formule: C₁₉H₁₄D₅NO₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C19H19NO2/c1-15(14-17-10-6-3-7-11-17)19(22)20-18(21)13-12-16-8-4-2-5-9-16/h2-13,15H,14H2,1H3,(H,20,21,22)/b13-12+/i2D,4D,5D,8D,9D
• Code InChI: InChIKey=SMUFHBOCNIUNPT-LBAVIFQTSA-N
• SMILES: [2H]c1c([2H])c([2H])c(NC(=O)/C(=C\c2ccccc2)C(=O)C(C)C)c([2H])c1[2H]