JI-​101

CAS : 900573-88-8

Ref. TR-J210340

Informations sur le produit

• Nom: JI-​101
• Synonymes: 1-[1-[(2-Aminopyridin-4-yl)methyl]-1H-indol-4-yl]-3-(5-bromo-2-methoxyphenyl)urea, CGI 1842
• CAS: 900573-88-8

Description

Applications JI-​101 is VEGFR2 inhibitor. It can be used as analyte in pharmacological activity and analytical study of assay methodologies and perspectives for quantitation of VEGFR2 inhibitors such as sunitinib, sorafenib, pazopanib and JI-101 which were involved in treatment of cancer in human and animal models including mouse.
References Sharma, K., et al.: Biomed Chromatogr, 29, 803 (2015)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 466.33
• Formule: C₂₂H₂₀BrN₅O₂
• Couleur/Forme: Pale Brown Solid
• InChI: InChI=1S/C22H20BrN5O2/c1-30-20-6-5-15(23)12-18(20)27-22(29)26-17-3-2-4-19-16(17)8-10-28(19)13-14-7-9-25-21(24)11-14/h2-12H,13H2,1H3,(H2,24,25)(H2,26,27,29)
• Code InChI: InChIKey=ZXBFYBLSJMEBEP-UHFFFAOYSA-N
• SMILES: COc1ccc(Br)cc1NC(=O)Nc1cccc2c1ccn2Cc1cc[nH]c(=N)c1