Kartogenin-d4

CAS : 4727-31-5

Ref. TR-K139802

Informations sur le produit

• Nom: Kartogenin-d4
• Synonymes: 2,3,4,5-tetradeuterio-6-[(4-phenylphenyl)carbamoyl]benzoic acid

Description

Applications Labelled Kartogenin (K139800). Kartogenin is a potent, selective, and non-cytotoxic downstream RUNX1 and RUNX2 modulator. Kartogenin causes mesenchymal stem cells found in joints to differentiate into chondrocyte cells that can build cartilage where it has been destroyed.
References Ruschig, H., et al.: Arzneim.-Forsch. Drug Res., 23, 1745 (1973), Hartmann, R., et al.: J. Med. Chem., 35, 2210 (1992), Kishida., et al.: Biochemistry, 45, 783 (2006),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 321.363
• Formule: C₂₀D₄H₁₁NO₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)/i4D,5D,8D,9D
• Code InChI: InChIKey=SLUINPGXGFUMLL-DOGSKSIHSA-N
• SMILES: [2H]c1c([2H])c([2H])c(C(=O)Nc2ccc(-c3ccccc3)cc2)c(C(=O)O)c1[2H]