rac-Kavain

CAS : 3155-48-4

Ref. TR-K145490

Informations sur le produit

• Nom: rac-Kavain
• Synonymes: 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, (E)-(±)-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (±)- (8CI), (±)-Kavain, (±)-Kawain, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, (E)-, DL-Kawain, dl-Kavain, (+)-Kavain, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, (E)-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (±)-, 4-methoxy-6-[(E)-2-phenylethenyl]-5,6-dihydro-2H-pyran-2-one, 5,6-Dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one, <span class="text-smallcaps">DL</span>-Kawain
• CAS: 3155-48-4

Description

Stability Light and Moisture Sensitive
Applications rac-Kavain is the main kavalactone found in the roots of the kava plant. Kavain is known to exhibit anticonvulsive properties by attenuating vascular smooth muscle contraction through interactions with voltage-dependent sodium and calcium channels. rac-Kavain was shown in recent research to exhibit protective properties on anaerobic glycolysis, ATP content and intracellular calcium and sodium of anoxic brain vesicles.
References Gleitz, J., et al: Neuropharmacol., 35, 1743 (1997); Hashimoto, T., et al.: Phytomedicine, 10, 309 (2003); Mulholland, P.J., et al.: Brain. Res., 945, 106 (2002);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 230.26
• Formule: C₁₄H₁₄O₃
• Couleur/Forme: Off-White to Light Yellow Solid
• InChI: InChI=1S/C14H14O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-8,10,12H,9H2,1H3/b8-7+
• Code InChI: InChIKey=XEAQIWGXBXCYFX-BQYQJAHWSA-N
• SMILES: COC1=CC(=O)OC(/C=C/c2ccccc2)C1