Kifunensine-13C2 ,15N

CAS : 109944-15-2

Ref. TR-K450002

Informations sur le produit

• Nom: Kifunensine-13C2 ,15N
• Synonymes: (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)-1,5,6,7,8,8a-hexahydro(4,5-13C2,315N)imidazolo[1,2-a]pyridine-2,3-dione, (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione, (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)imidazo[1,2-a]pyridine-2,3-dione, Fr 900494, Imidazo[1,2-a]pyridine-2,3-dione, hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-, (5R,6R,7S,8R,8aS)-, Imidazo[1,2-a]pyridine-2,3-dione, hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-, [5R-(5α,6β,7α,8α,8aα)]-, Kifunensine

Description

Applications Kifunensine-13C2 ,15N, is the labeled analogue of Kifunensine (K450000), which is a potent inhibitor of the mannosidase I enzyme and is primarily used in cell culture to make high mannose glycoproteins.
References Iwami, M., et al.: J. Antibiotic., 40, 612 (1987); Elbein, A.D., et al.: J. Biol. Chem., 265, 15599 (1990); Elbein, A.D., et al.: Archives of Biochem & Biophys., 288, 1, 177 (1991); Kayakiri, H., et al.: Chem. Pharm. Bull., 39(6), 1378 (1991);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 235.169
• Formule: C₂C₆H₁₂NNO₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C8H12N2O6/c11-1-2-3(12)4(13)5(14)6-9-7(15)8(16)10(2)6/h2-6,11-14H,1H2,(H,9,15)/t2-,3-,4+,5+,6+/m1/s1/i7+1,8+1,9+1
• Code InChI: InChIKey=OIURYJWYVIAOCW-BWRRVPNVSA-N
• SMILES: O=[13C]1[15NH][C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)N2[13C]1=O