Lamivudine (R)-Sulfoxide

CAS : 160552-54-5

Ref. TR-L172475

Informations sur le produit

• Nom: Lamivudine (R)-Sulfoxide
• Synonymes: GI138870X, 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, S-oxide, [2R-(2a,3b,5a)]-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-, [2R-(2a,3b,5a)]-, Gi 138870X

Description

Impurity Lamivudine EP Impurity H
Stability Hygroscopic
Applications Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 245.26
• Formule: C₈H₁₁N₃O₄S
• Couleur/Forme: Neat
• InChI: InChI=1S/C8H11N3O4S/c9-5-1-2-11(8(13)10-5)6-4-16(14)7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+,16+/m0/s1
• Code InChI: InChIKey=LJMQAXFNQNADRZ-AJHSIVBLSA-N
• SMILES: Nc1ccn([C@@H]2C[S@@](=O)[C@H](CO)O2)c(=O)n1