Lamivudine Tenofovir Monosoproxil Methane

CAS : 1904611-19-3

Ref. TR-L172485

Informations sur le produit

• Nom: Lamivudine Tenofovir Monosoproxil Methane
• Synonymes: ((Hydroxy((((R)-1-(6-((((1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)oxy)methyl Isopropyl Carbonate

Description

Applications Lamivudine Tenofovir Monosoproxil Methane is an analog of Emtricitabine Tenofovir Monosoproxil Dimer (E525065) and an impurity of both Lamivudine (L172500) and Tenofovir (T018500); both reverse transcriptase inhibitors and antiviral agents.
References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977); Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),; Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 644.59
• Formule: C₂₃H₃₃N₈O₁₀PS
• Couleur/Forme: Neat
• InChI: InChI=1S/C23H33N8O10PS/c1-14(2)40-23(34)37-12-39-42(35,36)13-38-15(3)6-30-11-28-19-20(26-10-27-21(19)30)25-9-24-16-4-5-31(22(33)29-16)17-8-43-18(7-32)41-17/h4-5,10-11,14-15,17-18,32H,6-9,12-13H2,1-3H3,(H,35,36)(H,24,29,33)(H,25,26,27)/t15-,17+,18-/m1/s1
• Code InChI: InChIKey=WWDKPARMTTZTHR-BPQIPLTHSA-N
• SMILES: CC(C)OC(=O)OCOP(=O)(O)CO[C@H](C)Cn1cnc2c(NCNc3ccn([C@@H]4CS[C@H](CO)O4)c(=O)n3)ncnc21