Lenvatinib

CAS : 417716-92-8

Ref. TR-L329400

Informations sur le produit

• Nom: Lenvatinib
• Synonymes: 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-, 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide, E 7080, ER 203492-00, Lenvima, 4-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide, 4-{3-Chloro-4-[(Cyclopropylcarbamoyl)Amino]Phenoxy}-7-Methoxyquinoline-6-Carboxamide, 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-, Er 203492-00, Lenvanix
• CAS: 417716-92-8

Description

Applications Lenvatinib is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
References Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 426.85
• Formule: C₂₁H₁₉ClN₄O₄
• Couleur/Forme: White To Beige
• InChI: InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
• Code InChI: InChIKey=WOSKHXYHFSIKNG-UHFFFAOYSA-N
• SMILES: COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O