(R)-Lofexidine

CAS : 81447-78-1

Ref. TR-L469395

Informations sur le produit

• Nom: (R)-Lofexidine
• Synonymes: 1H-Imidazole, 2-[(1R)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, 1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-, (R)-, 2-[(1R)-1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole, (-)-Lofexidine, Levlofexidine, Levlofexidine [INN], (-)-(R)-2-(1-(2,6-Dichlorophenoxy)ethyl)-2-imidazoline, Unii-5Spw497X0Z, 2-[(1S)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole, 2-[(1R)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole
• CAS: 81447-78-1

Description

Applications The R-enantiomer of Lofexidine. α2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive.
References Velly, J., et al.: J. Pharmacol., 8, 351 (1977), Jarrot, B., et al.: Biochem. Pharmacol., 28, 141 (1979), Birch, P., at al.: Brit. J. Pharmacol., 68, 107 (1980),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 259.13
• Formule: C₁₁H₁₂Cl₂N₂O
• Couleur/Forme: Neat
• InChI: InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)/t7-/m1/s1
• Code InChI: InChIKey=JHSPPBBJOLKJDH-UHFFFAOYSA-N
• SMILES: NCC1CN(Cc2ccc(F)cc2)CCO1