Loxoprofen

CAS : 68767-14-6

Ref. TR-L472905

Informations sur le produit

• Nom: Loxoprofen
• Synonymes: 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid, 2-[4-(2-Oxo-Cyclopentylmethyl)-Phenyl]-Propionic Acid, 2-[4-[(2-Oxocyclopentan-1-Yl)Methyl]Phenyl]Propionic Acid, 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic acid, 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoic Acid, A-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid, Alpha-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid, Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-, Ioxoprofen, Koloxo, Loxoprofen Acid, ��-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid

Description

Applications Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 246.30
• Formule: C₁₅H₁₈O₃
• Couleur/Forme: White To Off-White
• InChI: InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
• Code InChI: InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-N
• SMILES: CC(C(=O)O)c1ccc(CC2CCCC2=O)cc1