Lys-SMCC-DM1-D9

CAS : 1281816-04-3

Ref. TR-L488782

Informations sur le produit

• Nom: Lys-SMCC-DM1-D9
• Synonymes: (2S)-2-amino-6-[[4-[[3-[3-[[(2S)-1-[[(1S,2R,3R,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-3-oxopropyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]methyl]cyclohexanecarbonyl]amino]-2,3,3,4,4,5,5,6,6-nonadeuteriohexanoic acid
• CAS: 1281816-04-3

Description

Applications Lys-SMCC-DM1-D9 is deuterium labelled Lys-SMCC-DM1 (L488780). Lys-SMCC-DM1 (L488780) is designed to eradicate cancer cells that express the target antigen on their cell surface.
References Erickson, H., et al.: Bioconjugate Chem., 21, 84 (2010)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 1112.767
• Formule: C₅₃D₉H₆₆ClN₆O₁₅S
• Couleur/Forme: Neat
• InChI: InChI=1S/C53H75ClN6O15S/c1-29-12-11-14-40(72-8)53(70)27-38(73-51(69)57-53)30(2)46-52(4,75-46)41(26-43(62)59(6)36-23-33(22-29)24-37(71-7)45(36)54)74-50(68)31(3)58(5)42(61)19-21-76-39-25-44(63)60(48(39)65)28-32-15-17-34(18-16-32)47(64)56-20-10-9-13-35(55)49(66)67/h11-12,14,23-24,30-32,34-35,38-41,46,70H,9-10,13,15-22,25-28,55H2,1-8H3,(H,56,64)(H,57,69)(H,66,67)/b14-11+,29-12+/t30-,31+,32?,34?,35+,38+,39?,40-,41+,46-,52+,53+/m1/s1/i9D2,10D2,13D2,20D2,35D
• Code InChI: InChIKey=UBRZDBDIKWWPEN-OVNIJHAXSA-N
• SMILES: [2H]C([2H])(NC(=O)C1CCC(CN2C(=O)CC(SCCC(=O)N(C)[C@@H](C)C(=O)O[C@H]3CC(=O)N(C)c4cc(cc(OC)c4Cl)C/C(C)=C/C=C/[C@@H](OC)[C@@]4(O)C[C@H](OC(=O)N4)[C@@H](C)[C@H]4O[C@@]34C)C2=O)CC1)C([2H])([2H])C([2H])([2H])C([2H])([2H])[C@]([2H])(N)C(=O)O