N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-butanamide Sodium Salt

CAS : 198470-92-7

Ref. TR-M198470

Informations sur le produit

• Nom: N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-butanamide Sodium Salt
• Synonymes: Sodium Butyryl((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)amide, Parecoxib Impurity
• Marque: TRC

Description

Applications N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-butanamide Sodium Salt is potent and selective COX-2 inhibitor parecoxib Sodium for parenteral administration. Also, used in preparation of substituted benzenesulfonamide derivatives as prodrugs of COX-2 inhibitors.
References Talley, John J., et al.: PCT Int. Appl., (1997); Talley, John J., et al.: Journal of Medicinal Chemistry, 43, 1661-1663 (2000);

Propriétés chimiques

• Masse moléculaire: 406.431
• Formule: C₂₀H₁₉N₂NaO₄S
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H20N2O4S.Na/c1-3-7-18(23)22-27(24,25)17-12-10-15(11-13-17)19-14(2)26-21-20(19)16-8-5-4-6-9-16;/h4-6,8-13H,3,7H2,1-2H3,(H,22,23);/q;+1/p-1
• Code InChI: InChIKey=PUISERDKPKYJAH-UHFFFAOYSA-M
• SMILES: CCCC(=O)N([Na])S(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1