MDBN

CAS : 1485-00-3

Ref. TR-M199750

Informations sur le produit

• Nom: MDBN
• Synonymes: 5-(2-Nitroethenyl)-1,3-benzodioxole, 3,4-(Methylenedioxy)-ß-nitro-styrene, 1-(2-Nitrovinyl)-3,4-methylenedioxybenzene, 3,4-(Methylenedioxy)-ß-nitrostyrene, 3,4-Methylenedioxy-1-(2-nitrovinyl)benzene, 5-(2-Nitrovinyl)-1,3-benzodioxole, 5-(2-Nitrovinyl)benzodioxole, NSC 10120, NSC 105303, NSC 170724, 1,3-Benzodioxole, 5-(2-nitroethenyl)-, 1-(3,4-Methylenedioxy)phenyl-2-nitroethene, 3,4-Methylenedioxy-beta-nitrostyrene, 5-(2-Nitroethenyl)-1,3-Benzodioxole, 5-[(E)-2-nitroethenyl]-1,3-benzodioxole, 5-[(Z)-2-nitroethenyl]-1,3-benzodioxole, Styrene, 3,4-(methylenedioxy)-β-nitro-, Syk inhibitor III
• CAS: 1485-00-3

Description

Applications MDBN is a Src and Syk kinase inhibitor that prevents phosphorylation and cytoskeletal association of GPIIb/IIIa and talin.
References Wang, W., et al.: Mol. Pharmacol., 70, 1380 (2006); Chou, T., et al.: J. Biol. Chem., 286, 16546 (2011); Milhazes, N., et al.: Bioorg. Med. Chem., 14, 4078 (2006)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 207.229
• Formule: C₉H₇NO₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C10H13N3O2/c1-8(12(2)3)11-9-4-6-10(7-5-9)13(14)15/h4-7H,1-3H3/b11-8+
• SMILES: C/C(=N\c1ccc([N+](=O)[O-])cc1)N(C)C