Meleagrin

CAS : 71751-77-4

Ref. TR-M215335

Informations sur le produit

• Nom: Meleagrin
• Synonymes: (3E,7aR,12aS)-7a-(1,1-Dimethyl-2-propenyl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-4-ylmethylene)-12-methoxy-1H,5H-imidazo[1',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione, [7aR-(3E,7aR*,12aS*)]-7a-(1,1-Dimethyl-2-propenyl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-4-ylmethylene)-12-methoxy-1H,5H-imidazo[1',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione, 6-O-Demethyloxaline

Description

Applications Meleagrin is a is an antibiotic derived from the deep ocean and is identified as an inhibitor of the bacterial enoyl-acyl carrier protein reductase. (Fabl). Inhibits the growth of S. aureus, E.coli, and S.pneumoniae
References Shang, Z. et al.: Chin. J. Ocean. Limn., 30, 305 (2012);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 433.46
• Formule: C₂₃H₂₃N₅O₄
• Couleur/Forme: Light Yellow
• InChI: InChI=1S/C23H23N5O4/c1-5-21(2,3)22-11-18(29)20(31)27-17(10-14-12-24-13-25-14)19(30)26-23(22,27)28(32-4)16-9-7-6-8-15(16)22/h5-13,29H,1H2,2-4H3,(H,24,25)(H,26,30)/b17-10+/t22-,23-/m0/s1
• Code InChI: InChIKey=JTJJJLSLKZFEPJ-ZAYCRUKZSA-N
• SMILES: C=CC(C)(C)[C@@]12C=C(O)C(=O)N3/C(=C/c4cnc[nH]4)C(=O)N[C@]31N(OC)c1ccccc12