Mertansine

CAS : 139504-50-0

Ref. TR-M257800

Informations sur le produit

• Nom: Mertansine
• Synonymes: N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine, DM 1, Maytansinoid DM 1, N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine, N2′-Deacetyl-N2′-(3-mercapto-1-oxopropyl)maytansine, Maytansine, N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-

Description

Applications Mertansine is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 738.29
• Formule: C₃₅H₄₈ClN₃O₁₀S
• Couleur/Forme: Neat
• InChI: InChI=1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-22(14-19)16-24(45-7)30(23)36/h9-11,15-16,20-21,25-27,31,44,50H,12-14,17-18H2,1-8H3,(H,37,43)/b11-9-,19-10-/t20-,21+,25+,26-,27+,31-,34+,35+/m1/s1
• Code InChI: InChIKey=ANZJBCHSOXCCRQ-WFPGXDDLSA-N
• SMILES: COc1cc2cc(c1Cl)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCS)[C@]1(C)O[C@@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@H](OC)/C=C/C=C(\C)C2