4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide

CAS : 1061214-06-9

Ref. TR-M260090

Informations sur le produit

• Nom: 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
• Synonymes: Benzenesulfonamide, 4-[2-[1-(4-methylphenyl)ethylidene]hydrazinyl]-

Description

Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.
References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 303.38
• Formule: C₁₅H₁₇N₃O₂S
• Couleur/Forme: Neat
• InChI: InChI=1S/C15H17N3O2S/c1-11-3-5-13(6-4-11)12(2)17-18-14-7-9-15(10-8-14)21(16,19)20/h3-10,18H,1-2H3,(H2,16,19,20)
• Code InChI: InChIKey=JCRSPJLUSHTDDS-SFQUDFHCSA-N
• SMILES: C/C(=N\Nc1ccc(S(N)(=O)=O)cc1)c1ccc(C)cc1