1-α-Methyl Dapagliflozin

CAS : 714269-57-5

Ref. TR-M263010

Informations sur le produit

• Nom: 1-α-Methyl Dapagliflozin
• Synonymes: Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside, (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol, Methoxy Dapagliflozin, Methyl 1-C-[4-chloro-3-(4-ethoxybenzyl)phenyl]-α-D-glucopyranoside, Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-<span class="text-smallcaps">D</span>-glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-Glucopyranoside, α-<span class="text-smallcaps">D</span>-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, Methyl1-c-(4-chloro-3-((4-ethoxyphenyl)methyl)phenyl)-alpha-d-glucopyranoside

Description

Stability Hygroscopic
Applications 1α-Methyl Dapagliflozin is an antidiabetic agent and intermediate of Dapagliflozin (D226255]), a sodium-glucose transporter 2 inhibitor.
References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 438.90
• Formule: C₂₂H₂₇ClO₇
• Couleur/Forme: White
• InChI: InChI=1S/C22H27ClO7/c1-3-29-16-7-4-13(5-8-16)10-14-11-15(6-9-17(14)23)22(28-2)21(27)20(26)19(25)18(12-24)30-22/h4-9,11,18-21,24-27H,3,10,12H2,1-2H3/t18-,19-,20+,21-,22+/m1/s1
• Code InChI: InChIKey=GKTWLVVOULBRDU-XBOCFXMGSA-N
• SMILES: CCOc1ccc(Cc2cc([C@]3(OC)O[C@H](CO)[C@@H](O)C(O)[C@H]3O)ccc2Cl)cc1