5-Methyl-2’-O-methyluridine

CAS : 55486-09-4

Ref. TR-M263415

Informations sur le produit

• Nom: 5-Methyl-2’-O-methyluridine
• Synonymes: 2'-O-Methylribothymidine, 1-[(2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione, 2'-O-Methyl-5-methyl-D-uridine, 2′-O-Methylribothymidine, 5,2'-O-Dimethyluridine, 5-Methyl-2'-O-methyluridine, uridine, 5-methyl-2'-O-methyl-
• CAS: 55486-09-4

Description

Applications 5-Methyl-2’-O-methyluridine is one of three oligonucleotide in platinum-derivatized homopyrimidine triplex-forming oligonucleotides (Pt-TFOs) useful in crosslinking to the transcribed strand in the human androgen receptor (AR) gene. Inhibitory activity against M. bovis and M. avium.
References Graham, M. K., et al.: Biochem., 54, 2270-2282 (2015); Johar, M., et al.: Bioorg. Med. Chem., 13, 6663-6671 (2005)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 272.25
• Formule: C₁₁H₁₆N₂O₆
• Couleur/Forme: White to Off-White Solid
• InChI: InChI=1S/C11H16N2O6/c1-5-3-13(11(17)12-9(5)16)10-8(18-2)7(15)6(4-14)19-10/h3,6-8,10,14-15H,4H2,1-2H3,(H,12,16,17)/t6-,7-,8-,10-/m1/s1
• Code InChI: InChIKey=YHRRPHCORALGKQ-FDDDBJFASA-N
• SMILES: CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C)c(=O)[nH]c1=O