N-[(1R)-2-(Methoxymethylamino)-2-oxo-1-(phenylmethyl)ethyl]carbamic Acid 1,1-Dimethylethyl Ester

CAS : 115186-33-9

Ref. TR-M264380

Informations sur le produit

• Nom: N-[(1R)-2-(Methoxymethylamino)-2-oxo-1-(phenylmethyl)ethyl]carbamic Acid 1,1-Dimethylethyl Ester
• Synonymes: [(1R)-2-(methoxymethylamino)-2-oxo-1-(phenylmethyl)ethyl]carbamic Acid 1,1-Dimethylethyl Ester, [2-(Methoxymethylamino)-2-oxo-1-(phenylmethyl)ethyl]carbamic Acid 1,1-Dimethylethyl Ester, tert-Butyl [(1R)-1-Benzyl-2-[methoxy(methyl)amino]-2-oxoethyl]carbamate

Description

Applications N-[(1R)-2-(Methoxymethylamino)-2-oxo-1-(phenylmethyl)ethyl]carbamic Acid 1,1-Dimethylethyl Ester is an protected intermediate in the synthesis of Darunavir (D193500), a second generation HIV-1-protease inhibitor.
References Velmourougane, G., et al.: J. Med. Chem., 54, 1655 (2011);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 308.37
• Formule: C₁₆H₂₄N₂O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C16H24N2O4/c1-16(2,3)22-15(20)17-13(14(19)18(4)21-5)11-12-9-7-6-8-10-12/h6-10,13H,11H2,1-5H3,(H,17,20)/t13-/m1/s1
• Code InChI: InChIKey=ZAHRDPIWMGLOQJ-CYBMUJFWSA-N
• SMILES: CON(C)C(=O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C