3-O-Methyl-L-DOPA-d3 Monohydrate

CAS : 200630-46-2 586954-09-8

Ref. TR-M303817

Informations sur le produit

• Nom: 3-O-Methyl-L-DOPA-d3 Monohydrate
• Synonymes: 3-(Methoxy-d3)-L-tyrosine Monohydrate, 3-(Methoxy-d3)-4-hydroxyphenylalanine Monohydrate, 3-(Methoxy-d3)-DOPA Monohydrate, 3-(Methoxy-d3)-L-tyrosine Monohydrate, 3-O-(Methyl-d3)dopa Monohydrate, L-3-(Methoxy-d3)-4-hydroxy- phenylalanine Monohydrate, L-3-O-(Methyl-d3)-DOPA Monohydrate, L-4-Hydroxy-3-(methoxy-d3)phenylalanine Monohydrate, L-3-(4-Hydroxy-3-methoxy-d3-phenyl)alanine H2O

Description

Applications Labelled 3-O-Methyl-L-DOPA (M303815). 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.
References Soares-da Silva, P., et al.: Brain Res., 863, 293 (2000), Deleu, D., et al.: Clin. Pharmacokinet., 41, 261 (2002),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 232.24829
• Formule: C₁₀H₁₀D₃NO₄·H₂O
• Couleur/Forme: Neat
• InChI: InChI=1S/C10H13NO4.H2O/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14;/h2-3,5,7,12H,4,11H2,1H3,(H,13,14);1H2/t7-;/m0./s1/i1D3
• Code InChI: InChIKey=IDRRCKUGGXLORG-DZQKLOQPSA-N
• SMILES: O.[2H]C([2H])([2H])Oc1cc(C[C@H](N)C(=O)O)ccc1O