(AlphaR)-Alpha-Methyl-N-[(1R)-1-phenylethyl]benzenemethanamine Hydrochloride

CAS : 82398-30-9

Ref. TR-M326885

Informations sur le produit

• Nom: (AlphaR)-Alpha-Methyl-N-[(1R)-1-phenylethyl]benzenemethanamine Hydrochloride
• Synonymes: Bis((1R)-1-phenylethyl)amine Hydrochloride, [R-(R*,R*)]-α-Methyl-N-(1-phenylethyl)-Benzenemethanamine Hydrochloride, (R,R)-(+)-Bis(Alpha-Methylbenzyl)Amine Hydrochloride

Description

Applications (αR)-α-Methyl-N-[(1R)-1-phenylethyl]benzenemethanamine Hydrochloride is used in the synthesis of the highly potent anti-metastatic prostacyclin analogue Cicaprost (C432750). Also used in the synthesis of a key A-Ring intermediate in the preparation of 1α-fluoro vitamin D3 analogues.
References Lerm, M. et al.: J. Am. Chem. Soc., 125, 9653 (2003); Giuffredi, G. et al.: J. Org. Chem., 71, 5361 (2006);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 261.79
• Formule: C₁₆H₂₀ClN
• Couleur/Forme: White Solid
• InChI: InChI=1S/C16H19N.ClH/c1-13(15-9-5-3-6-10-15)17-14(2)16-11-7-4-8-12-16;/h3-14,17H,1-2H3;1H/t13-,14-;/m0./s1
• Code InChI: InChIKey=ZBQCLJZOKDRAOW-IODNYQNNSA-N
• SMILES: C[C@H](N[C@@H](C)c1ccccc1)c1ccccc1.Cl