Metopimazine

CAS : 14008-44-7

Ref. TR-M338760

Informations sur le produit

• Nom: Metopimazine
• Synonymes: 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide, 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl]-4-piperidinecarboxamide, 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide, 2-Methylsulfonyl-10-[3-(4-carbamoylpiperidino)propyl]phenothiazine, EXP 999, RP 9965, Vogalene, 1-{3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl}piperidine-4-carboxamide, 10-[3-(4-Carbamoylpiperidino)propyl]-2-(methanesulfonyl)phenothiazine, 14008-44-7, 4-Piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl]-, Exp 999, Isonipecotamide, 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]-, Rp 9965
• CAS: 14008-44-7

Description

Applications Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.
References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 445.60
• Formule: C₂₂H₂₇N₃O₃S₂
• Couleur/Forme: Off White Solid
• InChI: InChI=1S/C22H27N3O3S2/c1-30(27,28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)
• Code InChI: InChIKey=PGNHIDNQZQJIBF-HQCNSTIWSA-N
• SMILES: Nc1ccc(CS[C@@H]2OC(CO)[C@H](O[C@@H]3OC(CO)[C@H](O)C(O)C3O)C(O)C2O)cc1