MG 132

CAS : 133407-82-6

Ref. TR-M340900

Informations sur le produit

• Nom: MG 132
• Synonymes: (S)-N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-(1-formyl-3-methylbutyl)-L-leucinamide, Calpain inhibitor IV-2
• Marque: TRC

Description

Stability Hygroscopic
Applications MG 132 is a potent, membrane-permeable proteasome inhibitor. It induces neurite outgrowth in PC12 cells. Neuroprotective product.
References Lee, D., et al.: Trends in Cell Biol., 8, 397 (1998); Tsubuki, S., et al.: J. Biochem., 119., 572 (1996); Grimm, L., et al.: EMBO J., 15, 3835 (1996)

Propriétés chimiques

• Masse moléculaire: 475.62
• Formule: C₂₆H₄₁N₃O₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1
• Code InChI: InChIKey=VWUXBMIQPBEWFH-STSJHAPQSA-N
• SMILES: C[C@]12CC[C@H]3c4ccc(O)cc4C[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)[C@H]3[C@H]1CC[C@@H]2O