Midecamycin

CAS : 35457-80-8

Ref. TR-M343250

Informations sur le produit

• Nom: Midecamycin
• Synonymes: Leucomycin V, 3,4B-dipropanoate, Oxacyclohexadecane, leucomycin V deriv., Aboren, Antibiotic SF 837, Antibiotic SF 837A1, Antibiotic YL 704B1, Espinomycin A, Macropen, Medecamycin A1, Medemycin, Medemycin A1, Midecamycin A1, Midecin, Momicine, Mydecamycin, Mydecamycin A1, Myoxam, NSC 154011, Normicina, Platenomycin B1, Rubimycin, SF 837, SF 837A1, Turimycin P3, YL 704B1, (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-4-(Dimethylamino)-3-hydroxy-5-{[(2S,4R,5S,6S)-4-hydroxy-4,6-dimethyl-5-(propionyloxy)tetrahydro-2H-pyran-2-yl]oxy}-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl propanoate (non-preferred name), (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-4-(dimethylamino)-3-hydroxy-5-{[(2S,4R,5S,6S)-4-hydroxy-4,6-dimethyl-5-(propanoyloxy)tetrahydro-2H-pyran-2-yl]oxy}-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl propanoate (non-preferred name), 252-578-0, Antibiotic SF 837A₁, Antibiotic YL 704B₁, De 4',4''-Dipropionate (Ester), Leucomycin V 3,4B-Dipropanoate, Leucomycin V, 3,4^B-dipropanoate, Macro-Dil, Medecamycin A₁, Medemycin A₁, Midecamycin A₁, Mydecamycin A₁, Oxacyclohexadecane, leucomycin V deriv., Platenomycin B₁, SF 837A₁, Sf 837, Turimycin P₃, YL 704B₁

Description

Applications A 16-membered ring macrolide antibiotic used in ophthalmology as well as other medical fields.
References Matsui, K. et al.: J. Inter. Cytokin Res., 24, 197 (2004); Schmalreck, A.F. et al.: Antiinfect Drugs Chemother., 14, 225 (1996); Tokuda, H. et al.: Chemother., 21, 887 (1973);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 813.97
• Formule: C₄₁H₆₇NO₁₅
• Degré de pureté: >85%
• Couleur/Forme: Off-White
• InChI: InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3/b14-13+,17-15+/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38+,39+,40+,41-/m1/s1
• Code InChI: InChIKey=DMUAPQTXSSNEDD-PKSLHKBKSA-N
• SMILES: CCC(=O)O[C@H]1[C@H](C)O[C@@H](O[C@@H]2[C@@H](C)O[C@@H](O[C@@H]3[C@@H](OC)[C@H](OC(=O)CC)CC(=O)O[C@H](C)CC=CC=C[C@H](O)[C@H](C)C[C@@H]3CC=O)[C@H](O)[C@H]2N(C)C)C[C@@]1(C)O