Mocetinostat

CAS : 726169-73-9

Ref. TR-M481090

Informations sur le produit

• Nom: Mocetinostat
• Synonymes: N-(2-aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamide, Mg 0103, Mgcd 0103, N-(2-Aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide, N-(2-aminophenyl)-4-((4-pyridin-3-ylpyrimidin-2-ylamino)methyl)benzamide, N-(2-aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide, benzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-

Description

Applications Mocetinostat is a multi-targeted histone deacetylase inhibitor used in cancer therapy. Mocetinostat is undergoing clinical trials for the treatment of various cancers including follicular lymphoma, Hodgkin’s lymphoma and acute myelogenous leukemia.
References Ai, T., et al.: Curr. Med. Chem., 19, 475 (2012); Cacasin, M.A., et al.: Circulation Rsch., 110, 739 (2012); Younes, A., et al.: Lancet Oncol., 12, 1222 (2011);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 396.44
• Formule: C₂₃H₂₀N₆O
• Couleur/Forme: Neat
• InChI: InChI=1S/C23H20N6O/c24-19-5-1-2-6-21(19)28-22(30)17-9-7-16(8-10-17)14-27-23-26-13-11-20(29-23)18-4-3-12-25-15-18/h1-13,15H,14,24H2,(H,28,30)(H,26,27,29)
• Code InChI: InChIKey=HRNLUBSXIHFDHP-UHFFFAOYSA-N
• SMILES: Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1