2,3-Naphthalic Anhydride

CAS : 716-39-2

Ref. TR-N363000

Informations sur le produit

• Nom: 2,3-Naphthalic Anhydride
• Synonymes: benzo[f][2]benzofuran-1,3-dione, 1,3-ββ-Isonaphthofurandione, 2,3-Naphthalenedicarboxylic acid anhydride, 2,3-Naphthalenedicarboxylic anhydride, 2,3-Naphthalic anhydride, Naphtho[2,3-C]Furan-1,3-Dione
• CAS: 716-39-2

Description

Stability Moisture Sensitive
Applications 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.
References D’Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994); Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999); Parma, T., et al.: Nat. Med., 5, 582 (1999); Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 198.17
• Formule: C₁₂H₆O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C12H6O3/c13-11-9-5-7-3-1-2-4-8(7)6-10(9)12(14)15-11/h1-6H
• Code InChI: InChIKey=IZJDCINIYIMFGX-UHFFFAOYSA-N
• SMILES: O=C1OC(=O)c2cc3ccccc3cc21