Nifluridide

CAS : 61444-62-0

Ref. TR-N431580

Informations sur le produit

• Nom: Nifluridide
• Synonymes: N-[2-Amino-3-nitro-5-(trifluoromethyl)phenyl]-2,2,3,3-tetrafluoropropanamide, Compound 109168, EL 468, EL 968, L 27, L 27 (pesticide), N1-(2,2,3,3-Tetrafluoropionyl)-3-nitro-5-trifluoromethyl-o-phenylenediamine, N1-(2,2,3,3-Tetrafluoropropionyl)-3'-nitro-5'-trifluoromethyl-o-phenylenediamine, 6'-Amino-a,a,a,2,2,3,3-heptafluoro-5'-nitropropion-m-toluidide, N-[2-Amino-3-nitro-5-(trifluormethyl)phenyl]-2,2,3,3-tetrafluorpropanamid, propanamide, N-[2-amino-3-nitro-5-(trifluoromethyl)phenyl]-2,2,3,3-tetrafluoro-

Description

Applications Nifluridide also known as L-27 reduces the growth and metastasis of MCF-7 tumor cells in xenografts models and thus may provide a new therapeutic approach for the treatment of breast and other types of cancer. A potential KGFR tyrosine kinase inhibitor. Nifluridide is also used in several pesticidal and insecticide compositions.
References Kesinger, J. W., et al.: Anticancer Res., 35, 47 (2015); Borth, P. W., et al.: J. Econ. Entomol., 79, 1632 (1986)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 349.16
• Formule: C₁₀H₆F₇N₃O₃
• Couleur/Forme: Off-White
• InChI: InChI=1S/C10H6F7N3O3/c11-7(12)9(13,14)8(21)19-4-1-3(10(15,16)17)2-5(6(4)18)20(22)23/h1-2,7H,18H2,(H,19,21)
• SMILES: Nc1c(NC(=O)C(F)(F)C(F)F)cc(C(F)(F)F)cc1[N+](=O)[O-]