Nitisinone-13C6

CAS : 1246815-63-3

Ref. TR-N490137

Informations sur le produit

• Nom: Nitisinone-13C6
• Synonymes: 2-[2-Nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione-13C6, NTBC-13C6, Nitisone-13C6, Orfadin-13C6, SC 0735-13C6

Description

Applications Labelled Nitisinone. Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.
References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 335.18
• Formule: C₈C₆H₁₀F₃NO₅
• Couleur/Forme: Light Beige To Brown
• SMILES: O=C(c1ccc(C(F)(F)F)cc1[N+](=O)[O-])[13CH]1[13C](=O)[13CH2][13CH2][13CH2][13C]1=O