5-Nitro-8-hydroxyquinoline

CAS : 4008-48-4

Ref. TR-N496215

Informations sur le produit

• Nom: 5-Nitro-8-hydroxyquinoline
• Synonymes: 8-Quinolinol, 5-nitro-, 5-(Hydroxyl[oxido]amino)-8-hydroxyquinoline, 5-Nitro-8-oxychinoline, 5-Nitro-8-oxyquinoline, 5-Nitro-8-quinolinol, 5-Nitrox, 5-Nitroxine, 5NOK, 8-Hydroxy-5-nitroquinoline, A 82, BAS 58, NSC 74947, NSC 74948, Nibiol, Nitroxolin, Nitroxoline, Noxibiol, 5Nok, 8-Nitroquinolin-5-Ol, 8-Quinolinol, 5-nitro-, Bas 58, Nitroxolina, Nsc 74947, Nsc 74948

Description

Applications 5-Nitro-8-hydroxyquinoline is an antimicrobial agent used for the treatment of urinary tract infection. 5-Nitro-8-hydroxyquinoline is also a potent and reversible inhibitor of cathepsin B. 5-Nitro-8-hydroxyquinoline has been shown to have anti-cancer activity.
References Mirkovic, B. et al.: ChemMedChem, 6, 1351 (2011): Jiang, H. et al.: Cancer Lett., 312, 11 (2011); Ghoneim, M.M. et al.: Bioelectrochemistry, 80, 162 (2011);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 190.16
• Formule: C₉H₆N₂O₃
• Couleur/Forme: Off White Solid
• InChI: InChI=1S/C9H6N2O3/c12-8-4-3-7(11(13)14)6-2-1-5-10-9(6)8/h1-5,12H
• SMILES: O=[N+]([O-])c1ccc(O)c2ncccc12