Noditinib-1

CAS : 799264-47-4

Ref. TR-N634200

Informations sur le produit

• Nom: Noditinib-1
• Synonymes: 1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine
• CAS: 799264-47-4

Description

Applications Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.
References Khan, P.M. et al.: ACS Med. Chem. Lett., 2, 780 (2011);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 287.34
• Formule: C₁₄H₁₃N₃O₂S
• Couleur/Forme: Off-White Solid
• InChI: InChI=1S/C31H46O6/c1-17(2)9-8-10-20(28(35)36)26-24(37-19(4)32)16-31(7)27(26)23(34)15-25-29(5)13-12-22(33)18(3)21(29)11-14-30(25,31)6/h9,15,18,21-24,27,33-34H,8,10-14,16H2,1-7H3,(H,35,36)/b26-20+/t18-,21-,22+,23?,24+,27-,29+,30-,31+/m1/s1
• Code InChI: InChIKey=DOCBWOTZOGLGKD-DCMODCDWSA-N
• SMILES: CC(=O)O[C@H]1C[C@@]2(C)[C@@H](/C1=C(\CCC=C(C)C)C(=O)O)C(O)C=C1[C@@]3(C)CC[C@H](O)[C@H](C)[C@H]3CC[C@]12C