Oltipraz

CAS : 64224-21-1

Ref. TR-O586050

Informations sur le produit

• Nom: Oltipraz
• Synonymes: 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione, NSC 347901, RP 35972, 3H-1,2-Dithiole-3-thione, 4-methyl-5-(2-pyrazinyl)-, 3H-1,2-Dithiole-3-thione, 4-methyl-5-pyrazinyl-, 4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione, 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione, 5-(2-Pyrazinyl)-4-methyl-1,2-dithiole-3-thione, Brn 0978110, Ccris 4048, Nsc 347901, Oltipraz [INN], Oltiprazum, Oltiprazum [INN-Latin], Rp 35972, Unii-6N510Jul1Y

Description

Applications Oltipraz is a synthetic, substituted 1,2-dithiole-3-thione previously used in humans as an antischistosomal agent. Animal studies have demonstrated that oltipraz is a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Oltipraz is now known to be used for tumor prevention purposes.
References Yu, Z., et al.: Diabetologia., 54, 922 (2011); Benson, A.B., et al.: J. Cell. Biochem. Suppl., 17, 278 (1993);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 226.34
• Formule: C₈H₆N₂S₃
• Couleur/Forme: Red Solid
• InChI: InChI=1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
• Code InChI: InChIKey=CKNAQFVBEHDJQV-UHFFFAOYSA-N
• SMILES: Cc1c(-c2cnccn2)ssc1=S