Ouabain-d3 (Major)

CAS : 630-60-4

Ref. TR-O714502

Informations sur le produit

• Nom: Ouabain-d3 (Major)
• Synonymes: (1β,3β,5β,11α)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide-d3, g-Strophanthin-d3
• Marque: TRC

Description

Applications Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);

Propriétés chimiques

• Masse moléculaire: 587.67
• Formule: C₂₉H₄₁D₃O₁₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13?,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26?,27-,28+,29-/m0/s1/i7D,11D2
• Code InChI: InChIKey=LPMXVESGRSUGHW-LDNAMDFKSA-N
• SMILES: [2H]C1=C([C@@H]2CC[C@]3(O)[C@@H]4CC[C@]5(O)C[C@@H](O[C@@H]6O[C@@H](C)[C@H](O)C(O)C6O)C[C@@H](O)[C@]5(CO)[C@H]4[C@H](O)C[C@]23C)C([2H])([2H])OC1=O